After Spud and Herb load supplies aboard Lucky Linda for a flight to a mining camp on a remote ranch in Arizona, a mysterious passenger also comes aboard for the trip. They soon discover that he is from Cuba and become so consumed with the fear that he might hijack the plane that they scramble around until they accidentally lock themselves out of the cockpit while in flight.

Triple A competes against Crawford Airlines for a U.S. Mail contract, and after Spud agrees to care for a baby, he must bring the child aboard Lucky Linda during a check flight with a postal inspector.

Mrs. Crawford takes out a big life insurance policy on Spud and Herb, making them think she is plotting to get rid of them, and they begin to see every mishap as an attempt on their lives. Distracted by worry, Herb roars off in Lucky Linda without thinking about how he does not know how to land, and it is up to Spud to talk him down safely.

After Herb takes what he thinks will be an important executive position with a major airline, Spud accepts Mrs. Crawford′s offer to merge Triple A Airlines with Crawford Airlines – but then Herb changes his mind about taking the new job.

After Ronnie threatens to foreclose on Lucky Linda, Herb secretly arranges for a friend to "steal" the plane in order to have more time to come up with the money to pay Ronnie — but complications ensue when Spud calls the police to report the plane stolen and Herb books a group of nuns for a charter flight to San Francisco before discovering that Lucky Linda really is missing

Spud and Herb hire new staff for Triple A Airlines and sign a contract with a rock'n'roll star to fly her to her next concert, then become very nervous when they realize the contract stipulates that if they do not get her to the concert on time it will cost them $100,000 — and then everything goes wrong during the flight.

Ronnie sabotages Triple-A Airlines by making a large but phony reservation with Triple A, leading Spud and Herb to hire away all of Crawford Airlines' employees – and Spud ends up posing as the bandleader Lawrence Welk.

Spud and Herb mistake a television commercial director for a Federal Aviation Administration inspector, then get the chance to audition for him as stunt flyers.

Spud and Herb get a passenger they think can put in a good word for Triple-A Airlines with British royalty, so Spud poses as an Englishman with an upper-class accent to make a good impression on the passenger. During the flight, they learn that the cargo they are carrying includes a shipment of nitroglycerine, and before they can figure out what to do with it, Lucky Linda runs low on fuel and Spud develops a case of the hiccups.

Spud and Herb fly prospective buyers to what they believe is a new real estate development in the desert, but it turns out to be a ghost town and the front for a gambling operation. The criminals take Herb hostage, so Spud decides to try to free him by posing as an old prospector who has just struck it rich.

Triple-A Airlines is hired to fly a burro and a bale of hay to Mexico, and Spud and Herb worry that they are inadvertently becoming involved in a marijuana smuggling ring.

To win the business of a gourmet club, Spud and Herb set up a restaurant service aboard Lucky Linda with Spud posing as a famous French chef.

Despite Herb′s strong objections, Spud agrees to fly a pregnant woman to San Francisco and unknowingly picks up a stowaway cat that also is pregnant – and while Spud and a passenger help the cat deliver a litter of kittens aboard Lucky Linda during the flight, Herb is left alone in the cockpit to fly the plane by himself.