When Dr. Bashir 'Bash' Hamed finds himself at the site of a tragic accident, his medical training takes over as he works to save the wounded. At York Memorial Hospital, the staff, including Dr. Magalie 'Mags' Leblanc, Dr. Theo Hunter, and Dr. June Curtis, treat patients from the accident while concerns arise about their Chief of Emergency Medicine, Dr. Jed Bishop.

When Bash and Mags work together to treat a patient with a tricky diagnosis, Mags realizes that Bash's experience as a doctor in Syria has led to an instinct-based approach. Head nurse Claire Malone is concerned that Dr. Bishop is already working following his accident. June struggles to put her foot down with Dr. Singh concerning the needs of a patient. Theo works to build a connection with Bash.

As Bash's future at the hospital hangs in the balance, he diagnoses a young patient with a rare disease that could have been prevented. Mags is faced with case she cannot solve, as June tries to keep her personal life private. Theo drives through the night to spend a day with his family in Sudbury, Ontario.

Dr. Bishop puts extra pressure on Bash, while Theo feels powerless when something happens to one of his daughters back home. A patient puts Mags' moral convictions to the test, June tries to improve her social skills.

Bash does his best to celebrate Eid with his sister, but she wishes they could continue the traditions they had back home. Theo treats a teenage patient who wants to avoid telling his parents why he's in the hospital.

An incident at work causes Bash to second-guess himself. Mags is inspired by a firefighter devoted to her work, even if it means risking her life on a daily basis. June must learn to work with others.

Bash must deal with an unexpected turn of events. Theo gets a surprise visitor at home and faces a closed-minded patient at work. Bash and Mags team up to help a patient from overseas, but face a language barrier.

Bash and Amira settle into a new environment. While at the hospital, Bash helps a worried couple expecting their first child. Dr. Bishop puts Mags to the test by personally evaluating her performance in the emergency department.

Bash provides medical care to a friend who is reluctant about treatment. Mags has her hands full with a young woman who seems to be withholding information. Dr. Bishop offers Mags an incredible opportunity.

When an explosion takes place near the hospital, Bash runs toward the danger. When a schoolgirl is brought into the hospital in cardiac arrest, Theo does everything he can to save her.

Bash finds himself connecting with an unlikely patient. Mags strives to find balance in her life. Theo has a difficult discussion with his wife. June attempts to connect with a closed-off teenage patient.

When a young mother addicted to opioids nearly dies, Bash must figure out whether she's using again, or if something else is causing her deadly symptoms. Mags tries to help a patient who isn't healing properly. June is blindsided by her father.

Bash and Mags race to save a woman with mysterious symptoms who was nearly killed by their team's medical error. Theo tries to help a gravely ill teen and his family deal with the possibility that medical hope has run out.