Three best friends from Los Angeles — hopeless romantic Melanie, cynical businesswoman Joy, and aging actress Victoria — are flying to Paris when their plane makes an emergency landing in Cleveland. Realizing that the social norms from SoCal no longer apply, and thrilled by their liberating possibilities in Ohio, they decide to celebrate a city that values “real women” and stay where they’re considered “hot.”

Joy tries to take advantage of her newfound appeal in Cleveland by dating a much younger man, but her new relationship ends up exposing an old secret. Meanwhile, Melanie encourages Elka to date again by helping her decide between a bevy of men. Victoria gets hooked on Big N Easy, where she goes for the savings and stays for so much more.

In celebration of their collective birthdays, the girls give each other the gift of a blind date with an eligible man.

Victoria's old flame, musician Johnny Revere (Huey Lewis), is inducted into the Rock and Roll Hall of Fame.

Melanie throws a party to meet their neighbors and she comes off as insulting to one of her next door neighbors (Wayne Knight), a columnist for The Plain Dealer, leading Melanie to fear that he'll write something negative about her. Meanwhile, Victoria gets a offer to do a commercial for underpants in Japan and Elka sports a dyed hairdo that draws criticism from Joy.

Melanie's mother and Victoria's father visit on the same weekend forcing them to see their parents in a new light; Elka brings Joy and her mother together.

Melanie's ex-husband Anders comes to town and she starts to have feelings for him again. Meanwhile, Elka tries to juggle relationships with two senior suitors (Carl Reiner, Tim Conway).

Victoria lends her acting expertise to a high school's production of "Romeo and Juliet"; Melanie's new romance causes a rift with Joy; Elka crashes funerals.

Melanie comes to regret her nosy nature when her son pays a visit; Elka helps Victoria campaign for sympathy votes after she's nominated for a Daytime Emmy.

When a tornado threatens to hit Cleveland, the ladies find way more than just shelter in Elka's secret storm cellar.