We're hitting the road with Dr. Oakley as she makes her way around the Yukon for house calls. We venture to a sled dog operation where Michelle performs routine vaccinations and exams on 26 huskies. A near fatal emergency call brings Dr. Oakley to her home clinic where she rapidly works on a dog with a face full of porcupine quills. Later, at her satellite clinic in Alaska, Dr. Oakley's improvising skills are put to the test as she turns foam piping into a wing splint for an owl named Aspen.

Dr. Oakley meets with an Alaskan local whose rescued pets include a reindeer with a hernia and a hungry moose. Michelle and daughter Maya vaccinate lynx kittens, while husband Shane is called away to help fight a wild forest fire.

Dr. Oakley pays a visit to the angriest muskox in the Yukon for a check-up, but he isn't surrendering without a fight. After an exhausting week, Dr. Oakley and the family head off for daughter Sierra's first caribou hunt, a Yukon rite of passage.

It's mating season and Dr. Oakley is busier than ever with a cow who can't seem to get pregnant and a tricky case of a young caribou bull with growths on his nose. This small infection could spread to the rest of the herd if it's not treated soon.

At the Discovery Park in Alberta, Sierra gets to see how her mom manages physical exams on big cats like jaguars and cheetahs. At the Calgary Zoo, Michelle and Sierra tend to baby meerkats. Before heading home, they tag wild sheep in the mountains.

Michelle makes a house call to a blind farmer whose goat hasn't been able to breed. When Michelle tries to find and relocate a herd of wild horses who have been roaming too close to the Alaskan Highway, the horses move dangerously close to a cliff.