Three years after the Bone Collector ended his career, Detective Lincoln Rhyme teams with NYPD officer Amelia Sachs to investigate a series of murders that suggest the killer's return and an unlikely team is born.

Lincoln and Amelia join forces to find a killer inspired by Greek mythology who is live-streaming murders. Meanwhile, the Bone Collector prepares a terrifying gift to celebrate Lincoln's return to work with his new partner.

When a young woman from an insular Russian community who witnesses a murder comes to Lincoln and Amelia for help, the case takes a shocking turn when the mysterious murder is linked to a cold case - the tragic disappearance of a teenage girl. Meanwhile, the Bone Collector's 'secret' is discovered.

A bizarre murder at a university research site thrusts Amelia and Kate into the world of post-mortem forensics. Lincoln explores new possibilities with the help of Sellitto's friend.

The Bone Collector challenges Lincoln, Amelia and the team with a trifecta of victims across the city. As the team races to solve the clue trails before it's too late, Lincoln must come to terms with the Bone Collector's real target - his own ego.

Lincoln and the team hunt a serial killer who stages perfect murders by brilliantly framing suspects in what appear to be open-and-shut cases. The hunt hits home when one of Lincoln's closest friends is accused.

Lincoln, Amelia and the team are tasked with tracking down an anonymous bomber, targeting a string of buildings all across Manhattan. Meanwhile, the marriage between The Bone Collector and his wife, Danielle, reaches a terrifying crossroad.

When a politician's teenage daughter is kidnapped for ransom, Lincoln, Amelia and the team race against time to rescue her before the unthinkable happens. Meanwhile, the team makes a startling discovery - The Bone Collector's true identity.

The Bone Collector's name and face are all over the news. Staying one step ahead of the team, The Bone Collector puts his ultimate revenge plan into action by targeting those closest to Lincoln, including Amelia.

Lincoln is forced to save his son Camden by putting himself at risk and confronting The Bone Collector in a deadly face-off, mano a mano.