In the series premiere, parish priest Don Matteo investigates a young man's apparent suicide.

The murder of a doctor is investigated.

Don Matteo's help is needed by a young woman, whose family is in financial distress and being blackmailed. The citizens, surprised about their priest's meetings with this beautiful woman, start to spread rumours.

Don Matteo investigates a drug ring that attacked an undercover police officer.

An inmate is killed in jail. Suspicion falls on a prisoner who claims to be not guilty, although his fingerprints were found on the murder weapon. A scorpion fight, organized by the citizens, points Don Matteo in the right direction.

Don Matteo is asked for help: Unfaithful wife Annalisa wants to save her marriage. Soon after this conversation she is found dead, her husband becomes main suspect. Don Matteo finds out that someone observed the victim.

A woman reports the disappearance of her baby, who suddenly disappeared from its cradle. The investigations initially turn towards the girl's ex-boyfriend, but Don Matteo has some suspicions about a couple who have just had their son baptized.

Police officers find Don Matteo, gun in hand, next to a dead body. What happened? During a fight with the killer, the weapon was pushed in the priest's hands while the real murderer escaped. Imprisoned Don Matteo starts to investigate.

A well known entrepreneur is being blackmailed. Suspicion falls on a landlord who had differences with him before. While Don Matteo aids police investigations, the entrepreneur's son is poisoned...

A film team comes to town. An actor is killed on the set - the gun was loaded with real bullets! The person responsible for the props seems to have a motive...

An accident occurs during a bus ride. The driver seems to be responsible, tests reveal that he had alcohol in his system. Rumours start to spread in town about the rivalry of two bus enterprises...

Another homicide in town: An employee of the research center is found dead. A fellow worker is suspected to have committed the crime, but Don Matteo's investigations point in a different direction.

Don Matteo prepares for a funeral when he finds out that the man, who passed away in an old people's home, didn't die a natural death. Suspicion falls on the victim's son's girlfriend, who offers to anonymously pay for the funeral.

Mr. Morabito has an affair. He buys a rare diamond as a gift for his lover and hides it from his wife - in an inconspicuous container. Mrs. Morabito gives this container - not knowing what really is inside - to Don Matteo, who plans to host a charity event.

A police officer who investigates a drug ring - incognito - is obviously discovered and violently punished by the gang. Don Matteo helps investigations.