Detective Joe Miller finds himself on a case involving two men that are found burned to death in a pawn shop, apparently involving a mysterious key and a deal gone bad. After receiving the key, Joe discovers that it is just one of nearly one hundred objects with supernatural powers and a link to a hidden motel room.

Joe Miller is on the run after being framed for his partner's murder. He joins forces with Legion member Jennifer Bloom to find the Object that will help find his daughter, Anna. Along the way they learn about the Room's mysterious past. Martin Ruber searches for an object to gain membership in the Order of the Reunification.

After discovering the existence of the Occupant of Room 10, Joe attempts to find him and another object that will allow him to access the Vault. Kreutzfeld hatches a plan that could destroy the world. Ruber has a vision while in the desert.