Hosts Kevin and Frankie Jonas introduce the 12 celebrity relatives who will be living under one roof and concealing their identity and lineage in the quest for the coveted $100,000 prize. Contestants are tasked with competing in a talent show for their first challenge, with one contestant ultimately facing elimination.

After the first elimination, contestants keep their friends close and their secrets closer as new alliances are formed, and more identities are revealed. This week’s challenge tests the senses, giving contestant’s clues about their fellow housemate’s identities they can only feel, not see. A close round of voting in the Voto Booth ends in another elimination with the remaining contestants one step closer to winning the $100,000 prize.

With 10 contestants remaining, alliances continue to form and be tested throughout the house as more guesses are made; the contestants split up into two teams and jump into the pool, with one contestant saying goodbye.

A fashion show challenge forces the players to create and show off a look centered around one item of clothing that reveals a clue about themselves; the winner of the challenge receives information about a fellow housemate.

Celebrities' relatives step outside their famous family member's shadow and live together under one roof, concealing their identity and lineage in the quest for their own fame and fortune.

Attached to a lie detector, contestants take turns sitting in the hot seat answering yes or no questions about their relatives; they must decide whether to tell the truth or lie, while attempting to give their best poker face.

With only six contestants remaining, the competition is stiff, and loyalties are tested; this week's challenge is centered on a mock estate sale, where the contestants must spot the difference when certain items are swapped around.

An alliance is solidified between two housemates. One housemate continues to lead others on with her false identity. A trivia challenge tests pop-culture knowledge.

A challenge tests the contestants' knowledge about the celebrity relatives with clues pointing to their nicknames, careers, celebrity romances and TV appearances; the winner does not receive immunity but does receive the final wine room clue.