After breaking a quantum-interference device, mild-mannered comic book store owner Stuart Bloom must save the universe from imminent destruction.

Stuart, Bert, Denise, and Barry Kripke find themselves in what appears to be an ideal and peaceful Earth - that happens to be controlled by a repressive and vicious AI.

After the gang arrives in a world where magic is real, Bert discovers a natural gift for sorcery, while Kripke finds himself on his friend's bad side. Meanwhile, Stuart must enlist the help of one of this universe's most powerful wizards.

After landing in a mental hospital, Stuart questions whether his memories of hopping from universe to universe are the product of an overactive imagination...or psychotic illusion. Meanwhile, Kripke has a new love interest.

The gang arrives in paradise, where everyone lives in harmony with nature and each other. Bert finds true love and the machine is broken.

Emboldened after landing in a universe that looks and feels normal - except for one slight difference - Stuart takes a big leap forward with Denise. Meanwhile, Bert and Kripke team up to find a way out.

While attempting to steal a new piece of technology from Caltech, Stuart, Denise, Bert, and Kripke run into some very familiar visitors.

After being thrust into a world that is perpetually at war, Stuart must complete his mission before he and the rest of the gang can flee to safety.

After finding themselves trapped in a comic book, Stuart, Denise, Bert, and Kripke take advantage of their new surroundings to enlist the help of a superhero. The only problem...this world also has supervillains!