Yachiyo Inugami is a dog-like person who loves cats whilst Suzu Nekoyama is a cat-like person who loves dogs. Upon being introduced to each other by their mutual friend, Aki Hiiragi, the two take an instant interest in each other. Later, Yachiyo takes Suzu to her house to see her three pet dogs.

Yachiyo gets to know her classmate, Mikine Nezu, who displays a lot of mouse-like tendencies. Later, Mikine takes Yachiyo and Suzu to the biology club to meet her upperclassman, Yukiji Ushikawa, who is much like a cow.

Yachiyo brings in some tea spiked with catnip, hoping to make Suzu drink it and become docile and affectionate. However, when the tea is spilled on Suzu as a result of Aki's attempt to stop Yachiyo, she behaves in a more lewd manner than expected.

Following an eye exam, Yachiyo and Aki accompany Suzu to a glasses shop to get a new pair of glasses.

Not wanting Yachiyo to witness her first time doing karaoke, Suzu goes with Mikine for a practice run.

Suzu, on an errand for her sister, Tamaki, ends up encountering Yachiyo, Aki, and Aki's little sisters whilst shopping.

The class representative, Sora Sarutobi, has a hard time dealing with Yachiyo's antics.

A beautiful ghost makes herself known.

A lovers' quarrel for all the animals to see.

Everyone is excited for the pool opening except for a ghost and a cat.

A fever induced dream has real world effects.

Yukatas, shaved ice, and fireworks; It's a summer festival.