David and Gill and their son Freddie are hoping Noel can help their Labrador, Scooby, who has a life-threatening tumour in his leg. Noel goes to extraordinary lengths to save the life of Tiger the cat when his heart stops beating during recovery from an operation. When an emergency case of a lurcher called Otis with shotgun wounds to his leg comes in, Noel must extract the bullet before working out how to save the leg. And Noel has to come up with a way of helping a French bulldog with a fractured elbow to walk again =- does a pair of tights hold the answer?

Noel operates on a five-month-old rabbit called Rufus with a badly broken hind leg. He diagnoses that a much-loved cocker spaniel called Dixie needs major spinal surgery. And when young couple David and Khaya bring in Daphne, a three-legged dog they adopted from Thailand, after she had been attacked with a machete, Noel realises he must come up with a radical solution for the dog's remaining front paw, which is injured. Noel gains inspiration from X-Men's Wolverine for a daring solution.

A Staffie puppy called Jasper has a problem with his legs where they are growing in the wrong direction and out of shape. Noel must operate on him soon if they're to have any chance of correcting the problem. Much-loved Labrador Mojo has a spinal problem that means he must be operated on or face paralysis. And when a cat called Lolli, belonging to nine-year-old Lola, is brought in with a smashed pelvis, Noel must carry out a pioneering procedure to try to help her walk again.

Owner Diane brings in her 12-year-old cat Pixie, who's been hit by a car. Noel believes he can help Pixie walk again by giving her a revolutionary bionic implant. A Great Dane called Ellie has deformed bones and discs pressing down on her spinal cord. To give her some years of pain-free life, Noel implants bone marrow taken from the dog's shoulder into a special scaffolding in her neck, helping the vertebrae fuse together and relieve the pressure on her spine. Meanwhile, practice receptionist Natalie introduces a new arrival to the team.