Courtney and Eric Waldrop and their three lively boys get the shock of their lives when Courtney becomes pregnant with sextuplets; they face a high-risk delivery and the stress of becoming parents of nine kids overnight.

Courtney & Eric struggle through a high-risk delivery. Six premature babies must survive the NICU and prepare to come home during a national flu crisis. One baby takes a turn for the worse, as the family faces nonstop feedings and mounting expenses.