The sole survivor of an Army plane crash in the Peruvian hinterlands, Jim Ellison subsisted for nearly two years on his raw animal instincts. When he returned to America and became a police lieutenant, Jim discovered that the abilities that had kept him alive in the jungle now gave him extraordinary senses of perception. With the help of Captain Simon Banks and a grad student Blair Sandburg, Jim now attempts to use these powers to apprehend a terrorist bomber called the Switchman.

Garrett Kincaid, a notorious criminal that Jim Ellison had arrested years before, seizes control of Cascade's police station with the help of his gang of felons.

After witnessing the death of undercover officer Danny Choi at the hands of sniper Tommy Juno, Jim uses his vision to identify and apprehend the killer.

When Blair moves unknowingly into an apartment next to the drug lab of a gang, Jim finds himself embroiled in a gang war.

Blair and Jim, with forensics specialist Carolyn Plummer, suspect that a series of seemingly unrelated murders are actually the work of a serial killer.

Jim and Blair are assigned to escort Derek Wilson, a key witness in a local homicide case, on his train ride to the courthouse in Cascade.

While guest-lecturing in Blair's anthropology class, Jim saves the entire building from a deadly gas leak designed to distract the attention while a canister of the Ebola virus was being stolen from the hazardous materials lab.

After stopping an armored car heist, Ellison is struck by the high-tech weaponry at the criminals' disposal.

Jim's sentinel abilities detect something strange at the scenes of the recent jewelry robberies but he's unable to figure out what's causing the reaction.

As Blair forces Jim to a vacation at a remote monastery, Ellison begins to enjoy until one of the monks is found dead.