In the premiere of the true-crime series, the search for a missing escort leads the police on Long Island to discover the bodies of 10 women believed to have been murdered by the same killer.

The discovery of four women's bodies on Gilgo Beach is just the beginning, as investigators uncover multiple suspects and shocking theories while racing to identify the Long Island Serial Killer before he strikes again.

The mystery surrounding the disappearance of a 10-month-old girl from her Kansas City, Mo., home is examined. The family fears that she was abducted by a drifter, but the police suspect that someone within the family may be responsible.

Police question suspects in the inner circle of Jackie Galloway, a woman found strangled and bound with ritualistic knots; a chance encounter with a prowler leads them to the shocking discovery of a budding serial killer.

A long-cold case that may be heating up is examined. In 1981 Keddie, Cal., the investigation into the murders of a woman and three teens hits a wall. Fast forward three decades and recently discovered evidence may be key to cracking case.

Hikers discover the severed head of Hervey Medellin in the Hollywood Hills; the suspects include former lovers, drug cartel hit men and a porn star in this tale of lust, greed and butchery.

The 1995 murder of a 16-year old girl in Grand Prairie, Texas, goes unsolved for nine months, when a game of truth-or-dare leads to a startling confession.

An examination of the JonBenét Ramsey murder case. The 6-year-old beauty pageant winner was murdered in her family's home on Dec. 26, 1996. Included: whether she was killed in a kidnapping-gone-wrong, by a home intruder or by one of her own family.

A lone survivor is the only witness who can help police track down a serial killer known as the Grim Sleeper preying on women in South Central Los Angeles; after decades of searching, police hone in on an unlikely suspect.

In Craig, Ala., townspeople are shocked when police discover the charred body of beloved mother and wife Lauri Waterman; people have no idea who would want to kill her, then an unlikely witness reveals a sordid story of secrets and lies.

A brutal 1970 home invasion claims the lives of Army surgeon Jeffrey MacDonald's wife and daughters, leaving him the lone survivor; authorities doubt his story of murderous hippies and believe MacDonald committed the crime himself.