Nine-year-old Sheldon Cooper is a once-in-a-generation mind capable of advanced mathematics and science but learns that isn’t always helpful growing up in East Texas, a land where church and football are king.

To appease his worried mother, Sheldon employs the techniques of a self-help book to try and make a friend.

When George Sr. is rushed to the emergency room, Meemaw comes to babysit, and the kids have an adventure getting to the hospital on their own.

After choking on a breakfast sausage, Sheldon wrestles with his fear of solid foods and discovers comic books for the first time.

Sheldon struggles with newfound popularity after utilizing statistics to help the football team.

When a NASA representative visits Sheldon’s school and dismisses his science, Sheldon is set on a mission to prove him wrong.

The kids brainstorm ways to resolve a family feud when Meemaw refuses to give George Sr. her brisket recipe.

In an attempt to bond with Sheldon, George Sr. takes the boys on a road trip to see a space shuttle launch. Mary, Missy and Meemaw have a girls’ weekend at the salon.

George Sr. strikes a deal with Sheldon to tutor Georgie when poor grades threaten to keep him from playing football.

When Sheldon moves to Dallas to attend a school for gifted children, the family struggles to cope with his absence.

A worried Mary sends Sheldon to Sunday school after she finds him playing Dungeons and Dragons with his friends Tam and Billy.

Sheldon asks for a computer and unknowingly sparks a heated argument between Mary and George Sr. over the family’s finances.

When flu season hits Medford, Sheldon takes extreme measures to remain healthy.

When Mary takes a job as church secretary, she finds herself becoming Pastor Jeff’s marriage counselor. Also, Sheldon and Missy spend their first afternoon home alone.

Sheldon makes friends with an upperclassman who introduces him to a new field of science. Mary and George disagree on how to handle Sheldon’s blossoming social life.

A disappointing loss at the science fair sends Sheldon’s life in a new direction.

Sheldon is bullied by an unlikely character, and Mary and George disagree on how to handle the situation.

Mary bans Sheldon from reading a mature comic book. Sheldon decides it’s time to stop living under Mary’s thumb.

When Sheldon is no longer academically challenged at Medford High, he audits a college class taught by Dr. John Sturgis.

A battle erupts between the Coopers and Sparks when the Sparks’ new dog terrorizes Sheldon.

While Sheldon is busy keeping tabs on Meemaw’s budding relationship with Dr. Sturgis, George Sr. and Mary attempt to bond with their other children.

When Meemaw is pursued by two gentlemen callers, Sheldon interferes, forcing her to set some ground rules.