Tattooed snake-catching team Simon Keys and Siouxsie Gillett have had a hectic summer of catching snakes in Durban, South Africa. Today, their first call comes in an hour before sunrise, and it’s their most unusual job yet: snake on a train! Armed with grabsticks and flashlights, Simon and Siouxsie run alongside the train in the dark, jumping over trenches and signaling gear. It could be anything from a harmless house snake to a spitting cobra out hunting at night or even a black mamba that’s been disturbed. It’s a race against time. This train is leaving to pick up 200 passengers at the next station. A venomous snake on the train could spell disaster when the passengers board. Little do they know that the snake they’re looking for has deadly venom, which, drop for drop, is even more potent than that of the black mamba.

Snake bounty hunters Simon and Nadine are swamped with calls and hopeful that Mike, a friend and fellow snake-catcher in training, will prove a useful ally in their deadly deployments. After an already shaky start to the snake season, Mike and Simon head out to a local resident’s home to find a massive Burmese python sunning itself by the pool. This snake is strong, and Mike may have bitten off more than he can chew. The team then moves on to the next call, where they soon find themselves face to face with an angry female snake in defence mode, only to discover she may not be traveling alone.

Snake bounty hunters Simon, Nadine and Mike receive a frantic call from a father who has spotted a deadly black mamba in his yard. The team races to get to the scene before the man’s children return from school. With the venomous snake hiding high up in a tree, the snake hunters have to get creative if they want to catch it. The black mamba’s bite has a 100 percent fatality rate if left untreated, so being cautious is key to their success. Then they get a call from the fire department that a snake has been spotted in a house downtown. After a bit of commotion, the perpetrating snake is caught — and the team discovers that it’s nothing more than a harmless bush snake.